{"id":86965,"date":"2023-12-01T22:24:36","date_gmt":"2023-12-01T15:24:36","guid":{"rendered":"https:\/\/www.its.ac.id\/news\/?p=86965"},"modified":"2023-12-01T22:24:36","modified_gmt":"2023-12-01T15:24:36","slug":"its-professor-develops-supercritical-fluid-as-medicine-raw-material","status":"publish","type":"post","link":"https:\/\/www.its.ac.id\/news\/en\/its-professor-develops-supercritical-fluid-as-medicine-raw-material\/","title":{"rendered":"ITS Professor Develops Supercritical Fluid as Medicine Raw Material"},"content":{"rendered":"
\"Prof
Prof Dr Eng Siti Machmudah ST MEng when delivering her scientific oration about supercritical fluid at the ITS Professorial Inauguration procession<\/figcaption><\/figure>\n

ITS Campus, ITS News <\/b>– The use of organic compounds in the dissolution process of\u00a0 medicinal raw materials can pollute the surrounding environment. To overcome this problem, the\u00a0 178th Professor of the Institut Teknologi Sepuluh Nopember (ITS)<\/a> Professor Dr Eng Siti\u00a0 Machmudah B.Eng, M.Eng developed supercritical fluid technology as a medicinal raw material\u00a0 by processing herbal plants. <\/span><\/p><\/blockquote>\n

Through her scientific oration, the woman who is familiarly called Mach said that currently the\u00a0 raw materials for medicines in Indonesia are still dominated by imported products. Therefore, she\u00a0 made innovations in supercritical fluid in order to encourage the independence of medicinal raw\u00a0 materials in Indonesia. “In addition, the use of supercritical fluid technology can also be a solution\u00a0 to environmental problems,” he explained.\u00a0<\/span><\/p>\n

Furthermore, Mach explained that supercritical fluid is a compound that has exceeded its critical\u00a0 pressure point and critical temperature. This fluid, which has combined liquid and gas properties,\u00a0 functions as a pure solvent or medium for reaction or material separation processes. “Supercritical\u00a0 fluid can replace organic solvents in the separation process, so that the results obtained do not\u00a0 pollute the environment,” said the Professor of the Department of Chemical Engineering ITS.\u00a0<\/a><\/span><\/p>\n

In his process, Mach chose to use supercritical carbon dioxide (CO2) and subcritical water as\u00a0 compounds for his research. Both fluids were chosen because they are easy to obtain, non-toxic,\u00a0 and non-flammable. In addition, the use of CO2 can also reduce greenhouse gas emissions that\u00a0 trigger global warming.<\/span><\/p>\n

\"Prof
Prof Dr Eng Siti Machmudah ST MEng while conducting research in a laboratory at Tohoku University,\u00a0Japan<\/figcaption><\/figure>\n

Mach continued, these two compounds are used to extract raw materials for medicines from herbal\u00a0 plants. In her research, supercritical CO2 serves to extract raw materials for anticancer drugs from\u00a0 herbal plants, such as amygdalin from loquat fruit seeds. “Supercritical carbon dioxide can also be\u00a0 used for the micronization process of medicinal raw materials so that the drug delivery ability in\u00a0 the body can increase,” added the hijab-wearing woman.\u00a0<\/span><\/p>\n

In addition to amygdalin, the lecturer who was born in Gresik said that the use of supercritical\u00a0 CO2 can be used for other medicinal raw materials. Some of them are beta sitosterol, licopene,\u00a0 lutein, beta carotene, astaxanthin, and terpenoid compounds. Meanwhile, subcritical water can be\u00a0 used to obtain medicinal raw materials from herbal plants such as Moringa leaves and cat whiskers\u00a0 that can control blood pressure and treat inflammation.\u00a0<\/span><\/p>\n

Not only for medicinal raw materials, the alumnus of the doctoral program at Kumamoto\u00a0 University, Japan, initiated the use of supercritical CO2 technology for essential oil production.\u00a0 The oil, which is usually used for aromatherapy, can be produced from extracting plants that\u00a0 contain essential oils. “With supercritical CO2, the essential oil content in plants does not change\u00a0 in smell, color, or other physical properties,” Mach explained further.<\/span><\/p>\n

\"Prof
Prof Dr Eng Siti Machmudah ST MEng while conducting research in a laboratory at Tohoku University,\u00a0Japan<\/figcaption><\/figure>\n

To develop this innovation, the 50-year-old woman will continue to collaborate with the\u00a0 pharmaceutical industry to accelerate product downstreaming. The ITS Education Director also\u00a0 mentioned that the utilization of these innovations can be further developed not only in the\u00a0 pharmaceutical sector, but can also extend to the food industry and the cosmetics industry. <\/span>(ITS\u00a0 Public Relation). <\/b><\/p>\n

 <\/p>\n

Reporter: Muhammad Aulia Zikra<\/strong><\/p>\n

Translator: Niza Hakimatussayyidah Zaini Ramadhan<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

ITS Campus, ITS News – The use of organic compounds in the dissolution process of\u00a0 medicinal raw materials can pollute the surrounding environment. To overcome this problem, the\u00a0 178th Professor of the Institut Teknologi Sepuluh Nopember (ITS) Professor Dr Eng Siti\u00a0 Machmudah B.Eng, M.Eng developed supercritical fluid technology as a medicinal raw material\u00a0 by processing […]<\/p>\n","protected":false},"author":172,"featured_media":86872,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[67,125],"tags":[],"class_list":["post-86965","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-en","category-research-and-industry"],"yoast_head":"\nITS Professor Develops Supercritical Fluid as Medicine Raw Material - ITS News<\/title>\n<meta name=\"description\" content=\"Profesor ke-178 ITS, Prof Dr Eng Siti Machmudah ST MEng kembangkan fluida superkritis sebagai bahan baku obat dengan tanaman herbal.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.its.ac.id\/news\/en\/its-professor-develops-supercritical-fluid-as-medicine-raw-material\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ITS Professor Develops Supercritical Fluid as Medicine Raw Material - 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